The Ca(2+)-sensing receptor (CaSR) regulates Ca(2+) homeostasis in the body by monitoring extracellular levels of Ca(2+) ([Ca(2+)]o) and amino acids.Mutations at the hinge region of the N-terminal Venus flytrap domain (VFTD) produce either receptor inactivation (L173P, P221Q) or activation (L173F, P221L) related to hypercalcemic or hypocalcemic dis
Neurobrucellosis: three case reports and literature review
Background Brucellosis is a multisystem disease which may present with a broad spectrum of clinical manifestations and complications.Neurobrucellosis is an uncommon complication of this infection.This article aims to present clinical manifestations and to discuss the clinical features and management of 3 neurobrucellosis cases.Methods The diagnosis
Aerosol chemical composition at Cabauw, The Netherlands as observed in two intensive periods in May 2008 and March 2009
Observations of aerosol chemical composition in Cabauw, the Netherlands, are presented for two intensive measurement periods in May 2008 and March 2009.Sub-micron aerosol chemical composition was measured by an Aerodyne Aerosol Mass Spectrometer (AMS) and is compared to observations from aerosol size distribution measurements as well as composition
Mesoscopic Urban-Traffic Simulation Based on Mobility Behavior to Calculate NOx Emissions Caused by Private Motorized Transport
Motorized transport is one of the main contributors to anthropogenic CO 2 emissions, which cause global warming.Other emissions, like nitrogen oxides or carbon monoxide, are detrimental to human health.A prominent way to understand and thus be 3 nef runes able to minimize emissions is by using traffic simulations to evaluate different scenarios.In